Wednesday, 3 July 2013

Unique Histopathology picture/Bodies

Lesion/ Condition
Histopathological appearance
Actinomycosis
Organism arranged in Radiating rosette or Sunray pattern
Adenoid cystic carcinoma – cribriform pattern
Swiss cheese pattern or Honey comb pattern
Alveolar soft part sarcoma
Tumor cells in pseudoalveloar or organoid pattern
Apthous ulcer smear
Anitschkow cells
Aspergillosis
Organism are branching, septate hyphae invading blood vessels
Basal cell adenoma- membranous type
Neoplastic cells in Jigsaw puzzle pattern
Burkitt's lymphoma
Starry sky pattern
Calcifying epithelial odontogenic tumor
Lisegang rings – concentric calcifications
Calcifying Odontogenic cysts
Tumor cells have Ghost cells
Canalicular adenoma
Paired wall arrangement of neoplastic cells
Cat Scratch disease
Lymph node cortical hyperplasia; areas of stellate supparative necrosis surrounded by a band of histiocytes
Chronic diffuse sclerosing osteomyelitis
Bone shows mosaic pattern
Cicatricial pemphigoid
Sub-epidermal / sub-epithelial split; no acantholysis
Cytomegalovirus
Inclusion bodies makes the owl eyes cells
Dilantin sodium induced gingival hyperplasia
Test tube rete pegs
Epstein’s nodule
Keratin arranged in concentric “onion ring”
Ewing’s sarcoma
Neoplastic cells arranged in Filigree pattern
Family benign Pemphigus
Dilapidated brick wall effect; corps ronds and grain
Fibrosarcoma – intermediate
Herring bone pattern
Fibrous dysplasia
Chinese letter shaped bone trabeculae
Fibrous histiocytoma
Storiform pattern; Grenz zone
Gaucher’s disease
Gaucher’s cell with crumpled silk cytoplasm (liver cells)
Hemangiopericytoma
Stag horn pattern
Hereditary benign intraepithelial dyskeratosis
Cell with in a cell appearance -dyskeratotic epithelial cell
Hodgkins lymphoma
Lacunar type Reed Sternberg Cells – Owl eye cells
Hodgkins lymphoma – Nodular, lymphocyte predominant
Popcorn cells or Kern cells
Hurler syndrome
Hurler cells or Gargoyle cells or clear cells
Junctional nevus
"Abtropfung" effect
Keratosis follicularis
Corps ronds and grains
Lipoblastoma
Signet ring cells
Multiple myeloma
Russell cells;  sheets of plasma cells that have a cart wheel or checker board type of nuclear pattern
Mycosis fungoides
Mycosis cells or Sezary cells with cerebriform nucleus, Pautrier's micro abscess
Neurolemmoma
Antoni A; Antoni B; Verocay bodies
Niemann – Pick disease
Niemann –Pick cell in reticuloendothelial system as Sea-blue histiocyte
Oncocytoma
Oncocytes in alveolar or Organoid pattern
Paget's disiease
Jig jag or mosaic pattern of bones seem
Paracoccidiodiomycosis
Organism appears as a mickey mouse ears or Mariners wheel appearance
Para-neoplastic Pemphigus
suprabasilar split; Dyskeratotic cells
Pemphigus foliaceous
suprabasilar split, Antibodies to Desmoglein 1, Prevesicular edema, Tzank cells in smear; basal cells “ row of tombstones”
Pemphigus vulgaris
suprabasilar split, Antibodies to Desmoglein 1,3., Prevesicular edema, Tzank cells in smear; basal cells “ row of tombstones”
Pernicious anemia
Bone marrow biopsy - Erythroid precursors show checkerboard appearance
Polymorphous low grade adenocarcinoma
Indian filing pattern type of arrangement of neoplastic cells
Porokeratosis of Mibelli
Coronoid lamella
Radicular dentin dysplasia
Lava flowing over boulders
Rhabdomyosarcoma – Embryonal
Tadpole shaped rhabdomyoblasts
Rhabdomyosarcoma- pleomorphic
Spindle tumor cell appears as racquet / strug/ ribbon cells
Regional odontodysplasia
Enamloid congromerulates
Sarcoidosis
Schaumann bodies (Laminated basophilic calcifications), Asteroid bodies (Stellate inclusions in granulomatous inflammation)
Scurvy
Grustmark  and Trummerfield zone in bone
Synovial sarcoma
Appears like a developing joint with a typical synovium like cleft
Thalassemia
Intracellular inclusion bodies in erythrocytes - Fessas bodies –demonstrated by supravital stains; Target cell appearance; “safety pin cells”
Verruciform xanthoma
Foam cell limited to connective tissue papillae
Warty dyskeratoma
Corps ronds and grains
White spongy nevus
Eosinophilic condensation in perinuclear region of cells in superficial layers
Zygormycosis
Organism are large, branching, non septate hyphae invading blood vessels

More"Bodies"

·        Apoptotic bodies : membrane bound spherical structures in Apoptosis
·        Aschoff's bodies : Rheumatic fever
·        Asteroid bodies : Sporotrichosis; Sarcoidosis
·         Babes:Ernest metachromatic granules : Diphtheria
·         Balbiani's Bodies : yolk nucleus
·         Bamboo Bodies : asbestos bodies
·         Bollinger's bodies : Fowl pox (intracytoplasmic)
·         Brachy Wächter Bodies : Infective Endocarditis
·         Brassy Body : dark shrunken blood corpuscle found in MALARIA
·         Civatte’s (colloid) bodies : Lichen planus
·         Coccoid X Bodies : psittacosis
·         Councilman bodies : Yellow fever
·         Cowdry type:A bodies : Yellow fever, Herpes virus infection
·         Cowdry type:B bodies : Adenovirus, Poliovirus 
·         Davidson’s body : sex chromatin in neutrophils (dumbbell shaped); "Check Barr Bodies"
·         Döhle bodies : cytoplasmic inclusion bodies in neutrophils seen in bacterial infection
·         Donovan body : Granuloma inguinale
·         Feruginous Bodies : Asbestosis
·         Gamma-Favre bodies : LGV
·         Guarnieri's bodies : Vaccinia (intracytoplasmic)
·         Hectoid bodies : Sickle cell anemia
·         Heinz bodies – thalassemia; G6PD DEF
·         Henderson:Peterson's bodies : Molluscum contagiosum
·         Herring bodies : pars nervosa of pituitary gland
·         Hirano bodies : Alzheimer’s disease
·         Histiocytosis:X(HX)(Birbeck's granules) : Histiocytosis:X
·         Howell:Jelly bodies : splenectomy , Megaloblastic Anaemia, Hemolytic anaemia
·         LE bodies (hematoxylin bodies) : SLE
·         Leishman’s Donovan’s bodies : Kala Azar
·         Lewy bodies : Parkinson's disease
·         Lipschütz' bodies : intra nuclear inclusions in herpes simplex infection
·         Miyagava's bodies : Lymphogranuloma venereum
·         Moser’s bodies : Typhus fever
·         Mott Bodies : multiple myeloma
·         Negri bodies (intracytoplasmic, intra neuron, hippocampus) : Rabies
·         Nissl’s bodies : cytoplasmic inclusions in neurons
·         Odland Bodies : Flegel’s Disease (i.e hyperkeratosis lenticularis perstans); Keratinosome
·         Oken's Body : mesonephros
·         Pappenheimer bodies – non heme iron pigments in siderocyte
·         Paschen Bodies : variola or vaccinia
·         Pick BODIES : PICKS Disease
·         Red Neurons : Apoptosis
·         Reilly’s bodies : Hurler's syndrome
·         Residual Bodies : SARCOID AND SARCOID LIKE GRANULOMAS
·         Schaumann’s/Conchoids bodies (calcium & iron complexes) : Sarcoidosis & Berylliosis
·         Torres bodies : Yellow fever
·         Verocay bodies – Neurilemmoma; schwannoma
·         Weibel:Palade bodies : storage organelles of von Willebrand’s factor in platelets & endothelium
·         Winkler's & Ross's bodies : Syphilis
·         Zebra bodies : cytoplasmic inclusions in schwann cell degeneration
Zebra BODIES : Metachromatic Leukodystrophy, Niemann Pick's Disease.

3 comments:

  1. Thank you so much for this compiling material

    ReplyDelete
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