Tuesday, 2 July 2013

Definitions-1

No
What is….?
Answer…
1
Abfraction
 A regressive alteration of tooth structure usually involving hard tissue of the permanent dentition leading to loss of tooth surface at the cervical areas of teeth caused by tensile and compressive forces during tooth flexure. Alternatively, Cervical erosive lesions that cannot be attributed to any particular etiology
2
Abrasion
 A regressive alteration of tooth structure usually involving hard tissue of the permanent dentition leading to abnormal loss of tooth structure due to non-masticatory physical friction.
3
Abscess
 A localized accumulation of pus caused by an infection. Example periapical abscess.
4
Acantholysis
 A histopathological feature, characterized by loss of the intercellular bridges of the prickle cell layer (spinous) of the epithelium usually caused by accumulation of fluid or edema in between the keratinocytes.
5
Acanthosis
 A histopathological feature, characterized by excessive thickening of the intermediate cell layer or the stratum spinosum resulting in broadening and elongation of the rete pegs. It is considered as one of hall mark of epithelial dysplasia.
6
Acanthosis nigricans
 A rare acquired dermatological disease with an abnormal Keratinization process leading to development of velvety brownish alteration of skin. Sometimes this disease may be a marker of malignancy.
7
Accessory cusps
 A developmental anomaly of shape characterized extra cusp like the cusp of Caraebilli in maxillary first molar. 
8
Acidogenic theory
 It states that dental caries is a chemico-parasitic process consisting of two stages- the decalcification of enamel as a preliminary stage followed by dissolution of the softened residue. The acid required for decalcification is synthesized by the fermentation of starch and food residue by the bacteria’s. This theory was proposed by Miller.
9
Acinic cell adenocarcinoma
 A malignant salivary gland malignancy that salivary gland cells showing serous acinar differentiation, most commonly found in the parotid gland.
10
Acquired disturbances
 Disturbances in the structure or morphology of any organ form birth or during growth and can occur as a result of environmental or hereditary factors.
11
Acquired Immuno Deficiency Syndrome
 A syndrome caused by the infection of Human Immunodeficiency Virus causing the suppression of the immune system and predisposing the individual to infections.
12
Acral lentiginous melanoma
 A melanoma that is a brown in color irregularly shaped macular lesion that undergoes progression to nodular melanoma.
13
Acrodynia
  A chronic mercury exposure in infants and children where it produces a cold clammy skin, erythematous rashes, excessive salivation, and gingivitis may be the features of the condition.
14
Acromegaly
  A hormonal disorder that results when the pituitary gland produces excess growth hormone.
15
Actinic chelitis
 A chronic inflammatory lesion caused by chronic exposure to actinic or sunlight manifesting in skin of the middle and lower third of face and commonly in lower lips.
16
Actinic keratosis
 Is a common cutaneous premalignant lesion caused by exposure to ultraviolet radiation exposure with microscopic changes in epithelium and connective tissues.
17
Actinic lentigo
 Is a benign, multiple, freckle like lesion resulting from chronic exposure to ultraviolet damage to skin.
18
Actinomycosis
 Is an infection of filamentous, branching, gram positive anaerobic bacteria belonging to actinomycetes family. The supparative reaction is with yellowish sulphur like flecks that are the colonies of the organisms.  
19
Acute
  Of shorter duration. Usually have severe symptoms.
20
Acute necrotizing ulcerative gingivitis (ANUG)
  An infection of the gingiva caused by fusobacterium and Borecellia vincentii affecting inter- dental papillae as a punched out lesion covered by a pseudomembrane.
21
Acute osteomyelitis
 A rapidly destructive inflammatory process of bone and soft tissues associated with bone that usually consists of granulation tissue, purulent exudates, and islands of non-vital bone (sequestra).
22
Acute pulpitis
  An inflammation of the pulp caused by injury to the pulp, usually from dental caries or trauma. The thermal change (hot or cold) initiates the pain that is relived on removal of the noxious stimuli. It is usually either reversible or irreversible.
23
Addison´s disease
 A rare hormonal disorder that occurs when the adrenal glands do not produce enough of the hormone cortisol and less commonly aldosterone.
24
Adenoid squamous cell carcinoma
 A rare low grade histopathological variant of oral squamous cell carcinoma or in sun-exposed skin of the face and lower lip. The malignant cells are arranged in a gland like pattern.
25
Adenoma
 In Clinical terms refers to a glandular malignancy either benign or malignant. 
26
Adenomatoid odontogenic tumor
 An odontogenic tumor arising from epithelium and ectomesenchyme, well-circumscribed lesion that usually occurs around the crowns of unerupted anterior teeth of young patients and consists of epithelium in swirls and ductal patterns interspersed with spherical enamel like calcifications.
27
Adenosquamous carcinoma
  A rare, aggressive squamous cell carcinoma of the oral mucosa consisting of a mixture of malignant squamous and glandular cells.
28
Adult monostotic fibrous dysplasia
  A rare form of fibrous dysplasia occurring spontaneously in adulthood involving a single bone.
29
Adventious dentin
 The pathologically formed secondary dentin as a result of abnormal irritation.
30
Aerodontolgia
  A condition similar to pulpitis experienced in deep fillings in high altitudes is referred as aerodontalgia.
31
Agenesis
 Complete absence of an organ and its associated structures.
32
Agranulocytosis
  A marked decrease in the number of granulocytes (circulating or immature), particularly neutrophils.
33
Allergen
  A substance capable of inducing hypersensitivity or an allergic reaction.
34
Allergy
  A hypersensitive state acquired through exposure to a particular allergen. Re-exposure to the same allergen elicits an exaggerated reaction.
35
Alveolar cyst of new born
 They are small, superficial keratin filled cyst found in the alveolar mucosa of infants that arise from the remnants of the dental lamina.
36
Alveolar osteitis
 The destruction of initial clot usually after a traumatic extraction prevents the normal healing process causing the clinical condition of alveolar ostetits. Also known as dry socket.
37
Amalgam tattoo
  Oral soft tissue discolorations due to amalgam; most common exogenous pigmentation of the oral cavity.
38
Ameloblastic carcinoma
  An aggressive neoplasm of the jaws in which the epithelial cells exhibit histologic features of common ameloblastoma and malignancy.
39
Ameloblastic fibroma
  An odontogenic tumor arising from epithelium and ectomesenchyme, that is well circumscribed often located over unerupted molars in young patients; the connective tissue recapitulate primitive ectomesenchyme often found during various stages of odontogenesis.
40
Ameloblastic fibro-odontoma
  An odontogenic tumor arising from epithelium and ectomesenchyme, that has general features of ameloblastic fibroma but contains enamel and dentin. Alternatively it is an expansile odontogenic tumor in young patients that contains the soft tissue components of ameloblastic fibroma and the hard tissue components of complex odontoma.
41
Ameloblastic odontoma or odontoameloblastoma
  A rare odontogenic tumor that contains an ameloblastomatous component together with odontoma-like elements.
42
Ameloblastoma
 A unicentric neoplasm of odontogenic epithelium that is clinically benign, anatomically persistent, locally invasive and that has a wide spectrum of histologic patterns.
43
Amelogenesis
  The process of formation of the enamel portion of the tooth.
44
Amelogenesis imperfecta
 A spectrum of hereditary defects in the formation of ameloblasts and the mineralization of enamel matrix that results in teeth with multiple generalized abnormalities affecting the enamel layer only.
45
Amino acid
 An organic compound containing the amino group NH2. Amino acids are the main component of proteins.
46
Amyloidosis
 Represents a heterogeneous group of conditions characterized by the deposition of an extra cellular proteincious material called amyloid.
47
Anachoretic pulpitis
 Refers to the inflammation of pulp caused by agents reaching pulp through circulation.
48
Anaphylaxis
  A type of hypersensitivity or allergic reaction in which the exaggerated immunologic reaction results from the release of vasoactive substances such as histamine. The reaction occurs on re-exposure to a foreign protein or other substance after sensitization.
49
Anaplasia
 Lack of differentiation of cells
50
Anaplastic
 Refers to an adult cell that has changed irreversibly toward more primitive cell types and is often malignant.
51
Anemia
 A quantitative and or qualitative reduction of hemoglobin in blood. (Or) Reduction to less than normal of the number of red blood cells or quantity of hemoglobin or to the volume of packed red blood cells in the blood. (Or) Reduction in oxygen carrying capacity of blood. 
52
Anesthesia dolorosa
 An uncommon side-effect of surgical treatment of trigeminal neuralgia resulting in a combination of anesthesia and spontaneous pain of the facial skin.
53
Aneurysmal bone cyst
 An uncommon lesion (Pseudocyst) located primarily in the posterior mandible and maxilla with clinical features similar to central giant cell lesion often containing many large blood-filled spaces separated by connective tissue septa containing giant cell tissue and lined by epithelium.
54
Angiolipoma
 A benign tumor that consists of an admixture of mature fat and numerous small blood vessels.
55
Angioma
 A benign tumor made up of blood or lymph vessels.
56
Angiomatosis
  The process of subcutaneous vascular proliferation is referred to as angiomatosis.
57
Angioneurotic odema
 A diffuse edematous swelling of subcutaneous or submucosal soft tissues and is related to changes in vascular permeability due to mast cell granulation or C1 esterase deficiency.
58
Angiosarcoma
 Malignant, rare, rapidly growing lesion of endothelial cells that is more common in young patients and has a poor prognosis.
59
Angular chelitis
  It is an infectious diseases occurring along the corners of mouth caused by Candida, staphylococci or streptococci or a mixed infection. The lesion ulcerates and readily bleeds.
60
Anitschkow cell
 The cytologic smear of a recurrent apthous ulcer show a characteristic change in nucleus of epithelium with elongated nuclei containing a linear bar of chromatin. Such a cell is termed as Anitschkow cell.
61
Ankyloglssia
 A developmental anomaly of tongue characterized by an abnormal extensive adhesion of the tongue to the floor of the mouth or the lingual aspect of the anterior portion of the mandible caused by a short lingual frenum.
62
Ankylosed teeth
 Teeth that are fused to the alveolar bone by means of cementum; a condition especially common with retained deciduous teeth.
63
Anodontia
 Congenital condition in which all the teeth fail to develop.
64
Anomaly
 Any deviation from normal. May involve in composition, number, size, shape or structure.
65
Antibody
 A protein produced in the body in response to stimulation by an antigen. Antibodies react specifically to antigens in an attempt to neutralize these foreign substances.
66
Antigen
 A substance, usually a protein, which is recognized as foreign by the body's immune system and stimulates formation of a specific antibody to the antigen.
67
Antoni A tissue
 In neurilemoma, some of the neural tissue is regularly arranged in streaming fascicles of Schwann cells which often are palisaded and regularly arranged, refered as Antoni A tissue.
68
Antoni B tissue
 In neurilemoma, a part of the neural tissue is irregularly arranged in streaming fascicles of Schwann cells which often are less organized and less cellular refered as Antoni B tissue.
69
Apert’s syndrome or Acrocephalosyndactyly
 A rare craniosynostosis syndrome with characteristic features including acrobrachycephaly, Kleeblattschadel (clove leaf) deformity and syndactyly of second, third and fourth digits of limbs observed.
70
Apical peridontal cyst
 An odontogenic cyst of inflammatory origin that is preceded by dental caries and a chronic periapical granuloma and stimulation of rests of Malassez present in the periodontal membrane.
71
Aplasia
 Absence of an organ owing to lack of division of cells resulting in absence in that particular cells. Or Absence of an organ or a part of an organ due to failure of development of the embryonic tissue of origin or a defect in synchronous growth or a signaling molecule.
72
Aplastic anemia
 A rare type of life threatening hematological disorder characterized by failure of the hematopoeitic precursor cells to produce all blood cells, caused usually by the exposure to certain drugs, virus and carcinogens.
73
Apthous ulcer
  A recurrent ulcer of uncertain etiology. The chief etiological agents suggested include viruses, stresses and allergy. Includes a solitary large major variant and a multiple small minor variant.
74
Arrested caries
 A dental caries that has become static and does not show any tendency for further progression.
75
Asteroid bodies
 The granulomatous inflammation of sarcoidosis contains laminated stellate inclusions called as asteroid bodies.
76
Asymptomatic
 A lack of symptoms or complaints by the patient.
77
Atrophic
 A normally developed tissue that has decreased in size as compared to its normal size.
78
Atrophy
 Shrinkage in size of cell due to loss of cell substance.
79
Attrition
 A regressive alteration of tooth structure usually involving hard tissue of the permanent dentition leading to loss of tooth structure due to mechanical action of mastication. Is a physiological process when involving aged individuals and pathological in young patients.
80
Atypical
 Irregular, not conformable to the type.
81
Auspitz sign
 A Clinical sign in psoriasis wherein when the dry scales are removed forcefully reveals a one or more tiny bleeding spots.
82
Autoantibody
 An antibody that reacts against an antigenic constituent of the person's own tissues.
83
Autoimmune disease
 A disease or a lesion characterized by tissue injury caused by a humoral or cell-mediated immune response against constituents of the body's own tissues.
84
Autoimmunity
 Immune-mediated destruction of the body's own cells and tissues; immunity against self.
85
Autoinoculation
 To inoculate with a pathogen such as a virus from one's own body.
86
Autosomes
 The non-sex chromosomes those are identical for men and women.
87
B lymphocyte
 A lymphocyte -B cell (B for Bursa of fabricus in birds), that forms in bone marrow and matures without passing through the thymus. It matures into plasma cells that produce antibodies or Immunoglobulins.
88
Baby bottle syndrome
 See Rampant caries
89
Bacillary angiomatosis
 Is a multifocal subcutaneous vascular proliferation associated with cat scratch disease and often observed in patients with long standing HIV infection. They respond to erythromycin.
90
Ballooning degeneration
 The virus (Simplex virus) infected cell exhibit acantholysis, nuclear clearing and enlargement and is called as the ballooning degeneration.
91
Basal cell carcinoma
 A common, locally invasive, slow spreading, non metastasizing primary epithelial malignancy of the basal layer of skin and its appendages composed of medullary pattens of basaloid cells.
92
Basaloid squamous cell carcinoma
  Rare, aggressive form of poorly differentiated oral squamous cell carcinoma consisting of medullary patterns of cells with central areas of necrosis and resembles to basal cell carcinoma of skin.
93
Bell’s palsy
 Is an acute, often unilateral paralysis of the facial musculature with no proven cause.
94
Benign
 Not malignant; favorable for recovery.
95
Benign fibro-osseous lesions
 A heterotrophic collection of non-neoplastic intraosseous lesions that replaces normal bone and consists of a cellular fibrous connective tissue within which nonfunctional osseous structures form.
96
Benign fibrous histiocytoma
 A diverse group of benign neoplasm that exhibit both fibroblast and histiocytes and characterized by a storiform pattern with the spindle shaped fibroblast with vesicular nuclei predominating.
97
Benign lymphoepithelial cyst
 A lymphoepithelial cyst commonly located intraorally on the posterior lateral tongue and the anterior floor of the mouth inside the lymphoid tissue and is usually submucosal in its position.
98
Benign migratory glossitis
 A developmental anomaly of tongue characterized by multiple sensitive irregularly shaped erythematous patches on the tongue with arcuate white rims that enlarge and change shape daily.
99
Bifid condyle
 Is a rare developmental anomaly of head & neck region characterized by a double headed mandibular condyle. Fractures of condyle during growth may lead to bifid condyle.
100
Bifid uvula
 Is the most minimal manifestation of cleft palate and is limited to soft tissue structure of the uvula.
101
Biopsy
 Excision of a living tissue for the purpose of examination by a pathologist.
102
Black hairy tongue
 Is a developmental defect of tongue, characterized by marked accumulation of keratin on the filliform papillae of the dorsal aspect and associated with other conditions.
103
Blanching
 To take the color out of / Make white.
104
Bleopharochalasis
 Refers to the recurring edema of the upper eyelids leading to sagging of the lid at the outer canthus of the eye. It is a major component of the Ascher’s syndrome.
105
Blue nevus
 A benign pigmented epithelial pathology that presents as a dark blue dome-shaped papule or as a flat macule on the skin or mucosa. Made up of nevus cell and appears blue due to tyndallization effect.
106
Bohn’s nodules
 An uncommon superficial raised nodule scattered over the hard palate often near the border with the soft palate in infants that resolve without treatment; derived from rests of the dental lamina and consisting of keratin-producing epithelial lining.
107
Bony
 Composed of or containing bone.
108
Botryoid odontogenic cyst
 A slow-growing, non-expansile developmental odontogenic cyst derived from rests of the dental lamina resembling a bunch of grapes.  The cyst contains an embryonic lining of 1 to 3 cuboidal cells and distinctive focal thickenings (plaques).
109
Branchial cleft cyst
 An unusually large lymphoepithelial cyst located on the lateral aspect of the neck.
110
Brodie´s abscess
  A chronic abscess walled off in a sclerotic bone.
111
Bruxism
 A parafunctional masticatory habit related to stress or a sleep disorder, characterized by grinding one's teeth. May lead to attrition.
112
Buccal bifurcation cyst
 A cyst of uncertain origin found primarily on the distal or facial aspect of a vital mandibular third molar, consisting of intensely inflamed connective tissue and an epithelial lining.
113
Bulimia
  A psychiatric compulsive eating disorder characterized by episodic eating of large volumes of food, followed by purging behavior such as self-induced vomiting. This may cause erosion of the lingual aspect of mandibular anterior teeth.
114
Bull’s eye lesion
 Skin or mucous membrane lesions which are concentric rings resembling a circle within a circle; with a slightly depressed, dusky purple center, an elevated, surrounding macular erythema pale middle zone, and an erythematous border; usually associated with herpes simplex or erythema multiforme or drug eruption or mycoplasma infection.
115
Bulla (bullous/ bullae)
 A circumscribed elevated blister like lesion that is more than 5 mm in diameter, usually contains serous fluid.
116
Cabots rings
 A red blood cell abnormal feature observed in peripheral smear of pernicious anemia.
117
Café au lait spots
 Hyperpigmented lesions that may vary in color from light brown to dark brown. The borders may be smooth or irregular. Often found with fibrous dysplasia, neurofibromatosis and certain endocrine abnormalities.
118
Calcifying epithelial odontogenic tumor
 An odontogenic tumor arising from epithelium which is locally aggressive consisting of strands and medullary patterns of squamous and clear cells that are often accompanied by spherical calcifications (“Lisegang” ring) and amyloid-staining hyaline deposits. Also known as “Pindborg tumor”
119
Calcifying odontogenic cyst
 A rare, well-circumscribed, solid or cystic lesion derived from odontogenic epithelium that superficially resembles follicular ameloblastoma but contains "ghost cells" and spherical calcifications.
120
Cancrum oris
 Is rapidly progressive opportunistic infections of the normal oral flora during immunocompromised state and often begins as ANUG.
121
Candidiasis
 Encompasses a group of mucosal and cutaneous conditions with a common etiologic agent from the Candida genus of fungi; the most common oral mycotic infection.
122
Canker sores
  Also known as apthous stomatitits. It is a most common oral pathological ulceration attributed to many reasons. May present as a major, minor and recurrent forms.
123
Cannon’s disease
  See white spongy nevus
124
Capedont teeth
 Is a term given to teeth affected with dentinogenesis imperfecta.
125
Capsule
 Compressed fibrous connective tissue around a benign tumor or a cyst separating it from surrounding tissues.
126
Carcinogen
 A cancer causing agent.
127
Carcinogenesis
 The train of biological events that underlies development of neoplasia.
128
Carcinoma
 A malignant growth made up of epithelial cells that are capable of infiltration and metastasis.
129
Carcinoma in situ
 The most severe stage of epithelial dysplasia, involving the entire thickness of the epithelium, with the epithelial basement membrane remaining intact.
130
Caries, dental
 The microbial disease of teeth involving progressive demineralization of inorganic parts of tooth and followed by dissolution of organic material and modified by the saliva and dietary factors.
131
Carotid artery syndrome
 Is an abnormal developmental defect caused by the elongation of styloid process and or mineralization of stylohyoid ligament that leads to facial pain, dysphagia and transient syncope. Also known as Eagle’s syndrome.
132
Carotid body tumor
 Are the tumors that arise from the carotid body (chemoreceptors responsible for detecting changes in blood pH/ oxygen tension, at the bifurcation of carotids).
133
Carpet tack lesions
 In discoid lupus erythematosus, when the cutaneous scales are forcefully removed numerous extensions that had dipped in to the enlarged pilosebaceous canals. Such a lesion is described as carpet tack lesion.
134
Carrier
 In genetics, a heterozygous individual who is clinically normal but who can transmit a recessive trait or characteristic; also, a person who is homozygous for an autosomal dominant condition with low penetrance.
135
Cell-mediated immunity
 Immunity in which the predominant role is played by T lymphocytes.
136
Cellulitis
 A painful swelling of the soft tissue of the mouth and face resulting from a diffuse spreading of purulent exudate along the fascial planes that separate the muscle bundles.
137
Cementifying fibroma
 Also known as ossifying fibroma, cemento –ossifying fibroma. It is a well demarcated, osteogenic neoplasm that is composed of fibrous tissue that contain variable amount of calcified structure- bone and cementum in varying proportion.
138
Cementoblastoma
 A benign, well-circumscribed neoplasm of cementum-like tissue growing in continuity with the apical cemental layer of a tooth (often molar or premolar) that produce expansion of cortical plates and pain.
139
Cementoma, Familial gigantiform
 Is a synonym used for florid type of cemento-osseous dysplasia that occurs in a familial pattern as an autosomal inherited condition.
140
Cemento-osseous dysplasia
 Are a group of common fibro-osseous lesions in the jaw that have pathologic features similar to fibrous dysplasia.
141
Cemento-osseous dysplasia, florid
 A variant of cemento-osseous dysplasia that is found in the adult females and commonly in the afroamericans.
142
Cemento-osseous dysplasia, Focal
 A variant of cemento-osseous dysplasia that is found in the mandibular posterior region, usually in the middle aged females and with no racial predilection.
143
Cemento-osseous dysplasia, periapical
 A variant of cemento-osseous dysplasia that is found in the mandibular anterior periapical region, usually in the middle aged females and commonly in the afroamericans.
144
Cemento-ossifying fibroma
 A well-demarcated, encapsulated, expansile lesion of the jaws composed of cellular fibrous tissue containing spherical calcifications and irregular, randomly oriented bony structures and may be central or peripheral in location.
145
Central
 In Oral Pathology, a lesion occurring within Jaws.
146
Central giant cell lesion
 An intraosseous destructive lesion of the jaws in which lesions tends to expand the cortical plates, cause movement of teeth, and produce root resorption; composed of multinucleated giant cells in a background of mononuclear fibro-histiocytic cells and red blood cells. The cause may involve an abnormal calcium metabolism including renal and parathyroid gland pathology.
147
Central odontogenic fibroma
 An intraosseous benign neoplasm tissue of odontogenic origin (ectomesenchyme with or without epithelium) containing widely scattered islands and strands of embryonic odontogenic epithelium and calcifications.
148
Central papillary atrophy of tongue
 A form of erythematous candidal infection in the central part of the dorsum of tongue. Presents as a well demarcated erythematous zone that is often asymptomatic. It was previously thought to be a developmental anomaly of tongue.
149
Centromere
  The constricted portion of the chromosome that divides both the arms.
150
Cervical enamel projection
 Focal apical extensions of the enamel beyond the normally smooth cervical margin and on to the root of the tooth.
151
Chanchre
  Refers to the lesion of primary syphilis. Develops at the site of inoculation as a papular lesion with a central ulceration.
152
Cheesy
 Lesion’s texture is similar to curds of cheese.
153
Chemotaxis
 Taxis or movement in response to chemical stimulation. Often exhibited by the phagocytes.
154
Cherubism
 An autosomal dominant rare developmental fibro-osseous type of lesion of the jaws in children involving more than one quadrant and stabilizes after the growth period, usually leaving some facial deformity and malocclusion.
155
Chlorodontia
 A type of intrinsic greenish discoloration of teeth caused by accumulation of bilirubin that breaks in to biliverdin. This is formed during conditions hyperbilirubinemia.
156
Chondrosarcoma
 An uncommon malignant bone neoplasm in the jaws, usually of the anterior maxilla, consisting of a proliferation of chondroblasts or spindle-shaped mesenchymal cells and abnormal cartilage but no osteoid or bone.
157
Choriostomas
 Ectopic rests of non transformed tissues, not indigenous to that particular site. Or Is a tumor like growth of microscopically normal tissue in an abnormal location.
158
Chromatid
 Either of the two vertical halves of a chromosome that are joined at the centromere.
159
Chromatin
 A general term used to refer to the material (DNA) that forms the chromosomes.
160
Chronic
 Persisting over a longer duration; generally implies that there has been little change or extremely slow progression over a long period.
161
Chronic apical pulpitis
 An irreversible lesion located at the root apex showing the extension of the inflammatory process from the pulpal chamber. (Clinical; Radiological)
162
Chronic hyperplastic pulpitis (pulp polyp)
 An uncommon and specific type of inflammatory hyperplasia reaction of pulp to deep caries in a young person in which an inflamed hyperplastic pulp extends through a large carious lesion of a non-vital tooth.
163
Chronic osteomyelitis
 Prolonged inflammation of bone and soft tissues of bone including marrow, almost invariably due to infection.
164
Chronic pulpitis
 An inflammation of the pulp caused by injury to the pulp, usually from dental caries or trauma. The thermal change (hot) initiates the pain that is not relived on removing the noxious stimuli. It is usually irreversible and with a dull pain.
165
Chrysiasis
  Is a common complication of gold therapy that is manifested as a slate blue discoloration of sun exposed skin.
166
Chvosteks’s sign
 Is an oral finding observed in hypoparathyroidism. It is characterized by a twitching of upper lip when the facial nerve is tapped just below zygomatic process. It suggests a latent degree of tetany.
167
Clear cell
 A cell often associated with pathological lesions in hematoxycillin and eosin stain and which has a clear cytoplasm with a small peripherally located nucleus often due to accumulation of water, carbohydrate or proteins that do not take the stain.
168
Cleft lip
 A developmental defect of middle face characterized by the failure of fusion of median nasal process and maxillary process resulting in soft tissue abnormality.
169
Cleft palate
 A multifactorial developmental defect of the palate characterized by a lack of complete fusion of the two lateral portions of the palate, resulting in a communication with the nasal cavity.
170
Cleidocranial dysplasia
 A rare condition inherited as an autosomal dominant and characterized by partial or complete absence of the clavicles, defective ossification of the skull, and faulty occlusion due to missing, misplaced, or supernumerary teeth along with high arched palate.
171
Coagulation
  Refers to the process of clotting.
172
Codon
 The vertical sequence of three bases in DNA that codes for an amino acid. (Genetic)
173
Colley’s anemia
 Is also known as thalassemia major. It has a defective hemoglobin synthesis inherited through 2 defective genes for beta globin molecule causing microcytic, hypochromic anemia.
174
Commissure or the angle of mouth
 The junction of the upper and lower lips at the corner of the mouth.
175
Compound nevus
 The nevus characterized by a proliferation of nevus cells microscopically within the basal cell layer of the surface epithelium and involving the underlying connective tissue.
176
Concrescence
  A developmental anomaly or post inflammatory defect involving shape of teeth in which there is union of two adjacent teeth by cementum alone without the confluence of dentin.
177
Condyloma acuminatum
 Is a virus induced (HPV 6, 11, 16, 18) proliferation of the stratified squamous epithelium of the genetilia.
178
Condyloma lata
 Is a benign viral induced (HPV-2, 4, 40) hyperplasia of stratified squamous epithelium that appears as a painless papule or a nodule with a papillary projections.
179
Congenital
 Present at, or existing from the time of birth.
180
Congenital lip pits
 Autosomal dominant trait resulting in developmental defects involving the vermilion border of the lower and upper lip either at the central or the commissural area.
181
Consanguinity
 Blood relationship. In genetics, the term is generally used to describe marriages among close relatives.
182
Corps rands
 Refers to the peculiar round shaped dyskeratotic cells observed in Darrier’s disease.
183
Corrugated
  Descriptive term for a surface that appears wrinkled.
184
Cotton roll burn
 An iatrogenic injury caused by the oral mucosa become adherent to the dry cotton roll and their rapid removal from the mouth lead to stripping of the epithelium in the area.
185
Crouzon syndrome or Craniofacial dysostosis
 An uncommon, autosomal dominant craniofacial disorder characterized by craniosynostosis and dysmorphic facial features. The characteristic features include acrobrachycephaly, Kleeblattschadel (clove leaf) deformity and syndactyly of second, third and fourth digits of limbs observed.
186
Crowe’s sign
 Axillary freckling is known as crowe’s sign and observed in neurofibromatosis.
187
Cyst
 Is a pathologic epithelium-lined cavity, usually containing fluid or semisolid or gas. (Kramer)
188
Cystic hygroma
 Anomaly of the lymphatic system characterized by single or multiple cysts within the soft tissues, usually involving the head and neck.
189
Cytologic
 Pertaining to the scientific study of cells.
190
Cytology
 The scientific study of structures within the cell.
191
Cytopathologic
 Pertaining to or characterized by pathologic changes in cells.
192
Darrier’s disease
  An uncommon genodermatoses inherited as an autosomal dominant trait with defect in the adherence mechanism between surface squamous epithelial cell leading to acantholysis and characterized histopathologically by test-tube reteridges, corpsrands and grains.
193
Dead tracts
 Is a age related change in dentin, where in due to a trauma the odontoblastic process die and dentinal tubules are filled with air in section that appear as dark in transmitted light.
194
Degeneration
 Refers to the pathologic changes with cells which may to a certain extent reversible.
195
Delayed eruption
  The process of eruption of deciduous or permanent teeth very lately in relative to the normal age range.
196
Dens evaginatus
 A developmental anomaly in the shape of teeth in which a focal area of the crown projects outward and produces what appears as an extra cusp or an abnormal shape to existing cuspal arrangements. Often caused by an evagination of the crown during developmental stage.
197
Dens in dente
 "A tooth within a tooth"- A developmental anomaly in the shape of a malformed tooth caused by an invagination of the crown before it is calcified. (Or) An enamel-lined “pouch” extending apically from the lingual surface. It commonly affects maxillary lateral incisor teeth and manifests as an invagination on the lingual surface that may reach the pulp. Also known as Dens invaginatus.
198
Dental fluorosis
 A condition of enamel hypoplasia characterized by white chalky spots or brown staining and pitting of teeth due to an increased level of fluoride in affecting enamel matrix formation and calcification by the reaction of fluoride on the process of calcification.
199
Dental transposition
 A developmental anomaly characterized by a normal teeth erupting in to an inappropriate position.
200
Denticle
 A regressive alteration of teeth characterized by spherical calcification within the dental pulp lying free or attached to the pulpal surface of the tooth
201
Dentigerous cyst
 A common developmental type of odontogenic cyst associated with unerupted teeth and is caused by fluid accumulation between the reduced enamel epithelium and the enamel surface, resulting in a cyst in which the crown is located within the lumen and root(s) outside.
202
Dentin dysplasia
  A hereditary developmental defect in dentin formation in which the coronal dentin and tooth color is normal; the root dentin is abnormal with a gnarled pattern and associated shortened and tapered roots.
203
Dentinogenesis
 The formation of dentin.
204
Dentinogenesis imperfecta
 A hereditary defect consisting of opalescent teeth composed of irregularly formed and under mineralized dentin that obliterates the coronal and root pulpal chambers.
205
Denture epulis
 Is a tumor like hyperplasia of fibrous connective tissue that develops in association with the flange of an ill fitting denture.
206
Denture sore mouth
 Or Denture stomatitis. It is an erythematous or better a chronic atrophic candidiasis localized to denture bearing areas of maxillary denture.
207
Dermatofibroma
 Or fibrous histiocytoma. They are a diverse group of soft tissue benign tumors that exhibit both fibroblastic and histiocytic differentiation.
208
Dermoid cyst
 Is an uncommon developmental cystic malformation of the midline of the upper neck or the anterior floor of the mouth of young patients, derived from remnants of embryonic skin, consisting of a lumen lined by a keratinizing stratified squamous epithelium and containing one or more skin appendages such as hair, sweat, or sebaceous glands.
209
Desmoplastic fibroma
  A Benign diffuse infiltrative proliferation of fibroblasts leading to mature collagen deposition, occurring primarily within the mandible in young patients. A histopathological variant of fibroma.
210
Differential diagnosis
 A list of possible conditions that fit the information (history, signs, symptoms, radiological, laboratory and histopathological) derived from the patient
211
Differentiation
  The distinguishing of one thing from another. Or It is the extent to which neoplastic cells resemble their cell of origin.
212
Diffuse
 A term used to describe a lesion whose borders are not well defined or demarcated and is not possible to detect the exact parameters of the lesion.
213
Dilacerations
 A developmental anomaly manifested as an abnormal bend or curve. More commonly occurring in the root of a permanent tooth.
214
Diploid
 Having two sets of chromosomes; the normal constitution of somatic cells.
215
Distodens
 An accessory molar situated distally is called as distodens or distomolars.
216
Dominant
 A term often used in genetics. It means a trait or characteristic that is manifested when it is carried by only one of a pair of homologous chromosomes.
217
Donovan bodies
 Are the inclusion bodies in the cytoplasm of large mononuclear phagocyte in case of infection with Granuloma Inguinale, a chronic granulomatous infection. These bodies are tiny, elongated basophilic and arygrophilic rods and present in large numbers.
218
Donovan bodies
 Are tiny elongated basophilic and argyrophilic rods in the large mononuclear phagocytes in the intracytoplamc cysts in Granuloma inguinale.
219
Doorthy Reed cell
 Are the characteristic typically binucleated (owl eye nuclei) or multinucletated (pennies on plate) with prominent nucleoli in Hodgkins lymphoma.
220
Dorsal
  Directed toward / situated on the back surface (opposite of ventral).
221
Double lip
 A rare developmental anomaly commonly characterized by a horizontal fold of redundant mucosal tissue located on the inner aspect of the upper lip. May be congenital or acquired.
222
Down syndrome
 A common chromosomal disorder caused by the presence of an additional third chromosome in chromosome 21 and presents mild to moderate mental retardation and associated medical and dental problems.
223
Drug induced gingival hyperplasia
 Increased amount of gingiva. Generalized increase in the fibrous component of the gingiva in patients who have been taking long term doses of phenytoin, cyclosporine and nifedipine. Persistent dental plaque, calculus (tartar) and gingival irritation increase the severity of the hyperplasia.
224
Dry mouth
 Decreased saliva production. Also called as xerostomia.
225
Dry socket
 A clinical complication of traumatic tooth extraction. It occurs due to disintegration or loss of the blood clot, resulting in a dry appearance of the exposed bone in the socket.
226
Dysplasia
  An abnormality of development of any tissue. It is characterized by the loss of normal cellular architecture. In epithelium it is characterized by a disorderly development. Or  A non-neoplastic disorderly growth usually in epithelium.
227
Dystrophic calcifications
 Ectopic linear calcification within the pulp chamber of a tooth, the etiology of which is unknown. 
228
Eagle syndrome
 Is an abnormal developmental defect caused by the elongation of styloid process and or mineralization of stylohyoid ligament that leads to facial pain, dysphagia and transient syncope. Also known as carotid artery syndrome.
229
Eburnation of dentin
 An arrested caries of occlusal surface which is large and lacks food retention causing the superficially softened and decalcified dentin is burnished till it takes up a hard brown polished surface.
230
Ecchymosis
 Large reddish-blue areas in skin or mucous membrane caused by the escape of blood into the tissues, where it clots. It is commonly referred to as a bruise. Ecchymoses do not blanch on diascopy.
231
Ectodermal
 relates to the outermost of the three primitive germ layers of an embryo. Ectodermal derived structures include the skin, hair, nails, oral mucous membrane, and the enamel of the teeth.
232
Ectodermal dysplasia
 Relates to a group of inherited disorders where the ectodermal derivatives such as skin, sebaceous glands, hair, enamel and nails are malformed.
233
Edema
 Abnormal amounts of fluid in the intercellular spaces, resulting in visible swelling.
234
Edentulous
 The clinical absence of teeth.
235
Ehler-Danlos syndrome
 A group of inherited disorder of connective tissue that result in an abnormal connective tissue fibers especially collagen.
236
Embryonic
 Pertaining to the earliest stage of development of an organism.
237
Emigration
 The passage or white blood cells through the endothelium and wall of small blood vessels.
238
Enamel hypoplasia
 A defect in tooth enamel that results in less quantity of enamel than normal.
239
Enamel pearl
 Ectopic nodular deposits of enamel that primarily occur in the bifurcation or trifurcation areas on the roots of molars.
240
Enanthems
 Eruptions of mucous membrane.
241
Endodermal
 Pertaining to the innermost of the three primitive germ layers of an embryo. Endodermal structures include the epithelium of the pharynx, respiratory tract (except the nose), and the digestive tract.
242
Entropion
 In chronic inflammatory conditions of eye such as cicatrical pemphigoid, conjunctival vesicle heals with scarring leading the eye lids to turn inwards. Such a condition is referred as entropion.
243
Eosinophilic granuloma
 A pathological condition that has single or multiple bone lesion without visceral involvement, characterized by proliferation of histiocyte like Langerhans cells often affecting children.
244
Epidermoid cyst
 Is a common cyst of skin with a lumen lined by keratinizing stratified squamous epithelium, usually filled with keratin and without skin appendages in the capsule wall.
245
Epidermolysis bullosa
 Refers to a heterogeneous group of inherited blistering mucocutaneous disorders with a defect in attachment mechanisms of epithelial cells, either to each other or to the connective tissue.
246
Epithelial dysplasia
 A disorderly state of epithelium differentiation process characterized by a combination of individual cell and architectural alterations and is an indicator of the potentially malignant state.
247
Epithelium
  The cellular makeup of skin and mucous membranes.
248
Epstein’s pearls
 Uncommon superficial raised nodules on the midline of the hard palate of infants that resolve without treatment; derived from rests of the dental lamina and consisting of keratin-producing epithelial lining.
249
Epulis fissuratum
 A reactive lesion resulting in proliferation of fibrous connective tissue with an associated chronic inflammation in response to chronic injury such as an ill fitting denture.
250
Erosion
 The pathological wearing away of hard tissues of teeth through the action of chemical substances. . Also in histopathology refers to discontinuity or denudation of epithelium above the basal cell layer.

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